Rabbit Polyclonal Antibody to cdc25A(Phospho-Ser76)

Description
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

References
Jin J, et al. (2003) Genes 17(24): 3062-74.Shimuta K, et al. (2002) EMBO J 21(14): 3694-703.

Specification
Aliases	CDC25M3; MPIP1;
Entrez GeneID	993;
Swissprot	P30304
WB Predicted band size	70kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 76 (M-G-S(p)-S-E) derived from Human cdc25A.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100