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Western blot analysis of extracts from 293 cells untreated or treated with serum using cdc25C(Phospho-Ser216) Antibody P40116.

Immunofluorescence staining of methanol-fixed Hela cells using cdc25C(Phospho-Ser216) Antibody P40116.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using cdc25C(Phospho-Ser216) Antibody P40116(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to cdc25C(Phospho-Ser216)

货号：
P40116
别名：
CDC25M1; MPIP3;
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P30307
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to cdc25C(Phospho-Ser216)

Description
cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Description

cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

References
Toyoshima-Morimoto F. et al. (2002) EMBO Rep. 3(4): 341-348.Ferguson AM. et al. (2005) Mol Cell Biol. 25(7): 2853-2860.Donzelli M. et al. (2003) EMBO Rep. 4(7): 671-677.Chen F. et al. (2002) Proc Natl Acad Sci U S A. 99(4): 1990-1995.

Specification
Aliases	CDC25M1; MPIP3;
Entrez GeneID	995;
Swissprot	P30307
WB Predicted band size	60 80kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of serine 216 (S-P-S(p)-M-P) derived from Human cdc25C.
Formulation	Purified antibody in PBS with 0.05% sodium azide.