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Western blot analysis of extracts from HT29 and MDA cells untreated or treated with anisomycin using p53(Phospho-Thr18) Antibody P40093.
Rabbit Polyclonal Antibody to p53(Phospho-Thr18)
-
货号：
P40093 -
别名：
Antigen NY-CO-13; Phosphoprotein p53; TP53; Tumor suppressor p53; -
应用：
WB -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P04637 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Polyclonal Antibody to p53(Phospho-Thr18)
Description |
|---|
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. |
References |
|---|
| Lin T, et al. (2005) Nat Cell Biol; 7(2): 165-71.Vega FM, et al. (2004) Mol Cell Biol; 24(23): 10366-80.Li J, et al. (2004) J Biol Chem; 279(40): 41275-9.Wang J, et al. (2004) J Biol Chem; 279(38): 39584-92. |
Specification |
|
|---|---|
| Aliases | Antigen NY-CO-13; Phosphoprotein p53; TP53; Tumor suppressor p53; |
| Entrez GeneID | 7157; |
| Swissprot | P04637 |
| WB Predicted band size | 53kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of threonine 18 (Q-E-T(p)-F-S) derived from Human p53. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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