Rabbit Polyclonal Antibody to VEGFR2(Phospho-Tyr1214)

Description
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

References
Lamalice L, et al. (2004). Oncogene.23(2): 434-445. Takahashi T, et al. (2001). EMBO J .20(11): 2768-2778.

Specification
Aliases	FLK1; KDR; VGFR2; VGR2; kinase insert domain receptor
Entrez GeneID	3791;
Swissprot	P35968
WB Predicted band size	152kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of tyrosine 1214 (F-H-Y(p)-D-N) derived from Human VEGFR2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100
IF/ICC	1/100-1/200