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Western blot analysis of extracts from HUVEC cells using ICAM-1(Phospho-Tyr512) Antibody P40082(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
Western blot analysis of extracts from C2C12 cells, treated with starve or calf intestinal phosphatase (CIP), using ICAM-1 (Phospho-Tyr512) Antibody P40082.

Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)

  • 货号:

    P40082
  • 别名:

    ICA1; ICAM1;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P05362
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)

Description

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

References

Greenwood J, et al. (2003) J Immunol; 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem; 82(3):512-521

Specification

Aliases ICA1; ICAM1;
Entrez GeneID 3383;
Swissprot P05362
WB Predicted band size 89 92kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y(p)-R-L) derived from Human ICAM-1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P40082