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Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)
-
货号:
P40082 -
别名:
ICA1; ICAM1; -
应用:
WB -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P05362 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)
Description |
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ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
References |
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Greenwood J, et al. (2003) J Immunol; 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem; 82(3):512-521 |
Specification |
|
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Aliases | ICA1; ICAM1; |
Entrez GeneID | 3383; |
Swissprot | P05362 |
WB Predicted band size | 89 92kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y(p)-R-L) derived from Human ICAM-1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500-1/1000 |
Product Image
- Western blot analysis of extracts from HUVEC cells using ICAM-1(Phospho-Tyr512) Antibody P40082(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
- Western blot analysis of extracts from C2C12 cells, treated with starve or calf intestinal phosphatase (CIP), using ICAM-1 (Phospho-Tyr512) Antibody P40082.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P40082

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