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Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)

Western blot analysis of extracts from HUVEC cells using ICAM-1(Phospho-Tyr512) Antibody P40082(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).

Western blot analysis of extracts from C2C12 cells, treated with starve or calf intestinal phosphatase (CIP), using ICAM-1 (Phospho-Tyr512) Antibody P40082.

Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)

货号：
P40082
别名：
ICA1; ICAM1;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P05362
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)

Description
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

References
Greenwood J, et al. (2003) J Immunol; 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem; 82(3):512-521

Specification
Aliases	ICA1; ICAM1;
Entrez GeneID	3383;
Swissprot	P05362
WB Predicted band size	89 92kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y(p)-R-L) derived from Human ICAM-1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.