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Western blot analysis of extracts from A431 cells untreated or treated with EGF using HER2(Phospho-Tyr877) Antibody P40074.
Immunofluorescence staining of methanol-fixed MCF7 cells using HER2(Phospho-Tyr877) Antibody P40074.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using HER2(Phospho-Tyr877) Antibody P40074(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to HER2(Phospho-Tyr877)

  • 货号:

    P40074
  • 别名:

    C-erbB-2; ErbB2;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P04626
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to HER2(Phospho-Tyr877)

Description

Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin.

References

Dittadi, R. et al. (2000) J. Natl. Cancer Inst. 92, 1443-1444.Muthuswamy, S. K. et al. (1999) Mol. Cell. Biol. 19, 6845-6857.Qian, X. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 1500-1504.

Specification

Aliases C-erbB-2; ErbB2;
Entrez GeneID 2064;
Swissprot P04626
WB Predicted band size 185kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of tyrosine 877 (T-E-Y(p)-H-A) derived from Human HER2.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/100-1/200