Rabbit Polyclonal Antibody to Myc(Phospho-Thr58)

Description
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

References
Jin Z, et al. (2004) J Biol Chem. 279(38): 40209-40219.Welcker M, et al. (2004) Proc Natl Acad Sci U S A. 101(24): 9085-9090.Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702.Blackwood E M, et al. (1991) Science. 251:1211-1217.Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.

Specification
Aliases	c-myc
Entrez GeneID	4609;
Swissprot	P01106
WB Predicted band size	60kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of threonine 58 (L-P-T(p)-P-P) derived from Human Myc.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100