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Mouse Monoclonal Antibody to TSLPR
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货号:
32001 -
别名:
CRL2; TSLPR; CRLF2Y -
应用:
IHC,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q9HC73 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to TSLPR
Description |
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This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. |
References |
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1,PLoS One. 2019 Dec 12;14(12):e022465 2. 2,Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Aug;27(4):1058-1063. |
Specification |
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Aliases | CRL2; TSLPR; CRLF2Y |
Entrez GeneID | 64109 |
Swissprot | Q9HC73 |
clone | 1E10D3 |
WB Predicted band size | 42kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human TSLPR (AA: extra(23-231)) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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IHC | 1/200-1/1000 |
FCM | 1/200-1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
- Flow cytometric analysis of THP-1 cells using TSLPR mouse mAb (green) and negative control (red).
- Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using TSLPR mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded human rectal cancer tissues using TSLPR mouse mAb with DAB staining.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#32001

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