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All lanes : Anti-mouse BAD Antibody at 1:1000 dilution Lane 1: A20 whole cell lysate Lane 2: C2C12 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 22 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Mouse BAD Antibody (Center S112/S111/Y113) (Cat. #P34003) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the BAD antibody detected the BAD protein (arrow).

Rabbit Polyclonal Antibody to mouse BAD (Center S112/S111/Y113)

  • 货号:

    P34003
  • 别名:

    Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bad, Bbc6
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q61337
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to mouse BAD (Center S112/S111/Y113)

Description

BAD promotes cell death. It successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Specification

Aliases Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bad, Bbc6
Entrez GeneID 12015
Swissprot Q61337
WB Predicted band size 22.1kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen This mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of mouse BAD.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/1000