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All lanes : Anti-F11 Antibody (Center) at 1:1000 dilution Lane 1: A549 whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 70 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

F11 Antibody (Center) (Cat. #P33598)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F11 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Rabbit Polyclonal Antibody to F11

货号：
P33598
别名：
Coagulation factor XI, FXI, Plasma thromboplastin antecedent, PTA, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, F11
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P03951
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to F11

Description
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].

Description

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].

Specification
Aliases	Coagulation factor XI, FXI, Plasma thromboplastin antecedent, PTA, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, F11
Entrez GeneID	2160
Swissprot	P03951
WB Predicted band size	70.1kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This F11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-307 amino acids from the Central region of human F11.
Formulation	Purified antibody in PBS with 0.05% sodium azide.