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Rabbit Polyclonal Antibody to NCOA2
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货号:
P33423 -
别名:
Nuclear receptor coactivator 2, NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2, NCOA2, BHLHE75, SRC2, TIF2 -
应用:
WB -
反应种属:
Human, Mouse, Rat -
抗体类型:
Primary antibody -
Swissprot:
Q15596 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to NCOA2
Description |
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Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF- 2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK- ARNTL/BMAL1 heterodimer (By similarity). |
Specification |
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Aliases | Nuclear receptor coactivator 2, NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2, NCOA2, BHLHE75, SRC2, TIF2 |
Entrez GeneID | 10499 |
Swissprot | Q15596 |
WB Predicted band size | 159.2kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | This NCOA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1431-1462 amino acids from human NCOA2. |
Application |
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WB | 1/2000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P33423

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