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Rabbit Polyclonal Antibody to Mouse Kdm6a

All lanes : Anti-Kdm6a Antibody (C-term) at 1:2000 dilution Lane 1: mouse cerebellum lysates Lane 2: mouse spleen lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 154 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Rabbit Polyclonal Antibody to Mouse Kdm6a

货号：
P33056
别名：
Lysine-specific demethylase 6A, 11411-, Histone demethylase UTX, Ubiquitously transcribed TPR protein on the X chromosome, Ubiquitously transcribed X chromosome tetratricopeptide repeat protein, Kdm6a, Utx
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
O70546
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to Mouse Kdm6a

Description
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (By similarity).

Description

Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (By similarity).

Specification
Aliases	Lysine-specific demethylase 6A, 11411-, Histone demethylase UTX, Ubiquitously transcribed TPR protein on the X chromosome, Ubiquitously transcribed X chromosome tetratricopeptide repeat protein, Kdm6a, Utx
Entrez GeneID	22289
Swissprot	O70546
WB Predicted band size	154.4kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This mouse Kdm6a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1041-1074 amino acids from the C-terminal region of mouse Kdm6a.