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Western blot analysis of lysate from ZF4 cell line, using DANRE sh3bp4a Antibody (N-term)(Cat. #P32937). P32937 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Rabbit Polyclonal Antibody to (DANRE) sh3bp4a (N-term)

货号：
P32937
别名：
SH3 domain-binding protein 4-A, sh3bp4a, sh3bp4
产品上架时间：
2024-01-01
应用：
WB
反应种属：
zebrafish
抗体类型：
Primary antibody
Swissprot：
Q1LVQ2
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to (DANRE) sh3bp4a (N-term)

Description
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).

Description

Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).

Specification
Aliases	SH3 domain-binding protein 4-A, sh3bp4a, sh3bp4
Entrez GeneID	403082
Swissprot	Q1LVQ2
WB Predicted band size	108.5kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	zebrafish
Immunogen	This DANRE sh3bp4a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 132-165 amino acids from the N-terminal region of DANRE sh3bp4a.