Rabbit Polyclonal Antibody to LIM Kinase 1

Description
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.

Specification
Aliases	LIMK1; LIMK; LIM domain kinase 1; LIMK-1
Entrez GeneID	3984
Swissprot	P53667
WB Predicted band size	Calculated MW: 73 kDa; Observed MW: 73 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide of human LIMK1
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application
WB	1/500-1/1000