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Western blot analysis of HDAC5 in various lysates using HDAC5 antibody.

Western blot analysis of HDAC5 in K562 lysates using HDAC5 antibody.

Western blot analysis of HDAC5 in colo lysates using HDAC5 antibody.The lane on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using HDAC5 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Rabbit Polyclonal Antibody to HDAC5

货号：
P23154
别名：
HD5; NY-CO-9
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9UQL6
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to HDAC5

Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Specification
Aliases	HD5; NY-CO-9
Entrez GeneID	10014
Swissprot	Q9UQL6
WB Predicted band size	Calculated MW: 122 kDa; Observed MW: 122 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	The antiserum was produced against synthesized peptide derived from human HDAC5. AA range:464-513
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.