MSH2[31785]
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometric analysis of Hela cells using MSH2 mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to MSH2

  • 货号:

    31785
  • 别名:

    FCC1; COCA1; HNPCC; LCFS2; hMSH2; HNPCC1
  • 产品上架时间:

    2024-01-01
  • 应用:

    FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P43246
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to MSH2

Description

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

References

1.Anticancer Res. 2018 May;38(5):2841-2848.
2.Biochem Biophys Res Commun. 2015 Jan 2;456(1):506-12.

Specification

Aliases FCC1; COCA1; HNPCC; LCFS2; hMSH2; HNPCC1
Entrez GeneID 4436
Swissprot P43246
clone 4F10D6
WB Predicted band size 104.7kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#31785