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Western blot analysis of ADAM10 in NTERA-2 lysates using ADAM10 antibody.
Rabbit Polyclonal Antibody to ADAM10
-
货号：
P23095 -
别名：
CDw156; CD156c; ADAM10; KUZ; MADM -
应用：
WB,IP -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
O14672 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Polyclonal Antibody to ADAM10
Description |
|---|
The ADAM10 prodomain acts as a chaperone that stabilizes mature ADAM protein folding, and prevents target-protein shedding through inhibition of ADAM10 proteinase activity. Mature ADAM10 is the major α-secretase responsible for cleavage of Notch, APP, cadherins, and prion protein. The ADAM10 protein cleaves receptor tyrosine kinases and their associated ligands and displays a wide range of regulatory functions across related signaling pathways. |
Specification |
|
|---|---|
| Aliases | CDw156; CD156c; ADAM10; KUZ; MADM |
| Entrez GeneID | 102 |
| Swissprot | O14672 |
| WB Predicted band size | Calculated MW: 84 kDa; Observed MW: 90,68 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human ADAM10 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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