Rabbit Monoclonal Antibody to USP10

Description
Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.

Specification
Aliases	Deubiquitinating enzyme 10; UBPO; USP10
Entrez GeneID	9100
Swissprot	Q14694
WB Predicted band size	Calculated MW: 87 kDa; Observed MW: 110 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human USP10
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IP	1/10-1/20
IHC	1/50-1/100
IF/ICC	1/50-1/200