Rabbit Polyclonal Antibody to Rad50

Description
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.

Specification
Aliases	RAD50; DNA repair protein RAD50; hRAD50
Entrez GeneID	10111
Swissprot	Q92878
WB Predicted band size	Calculated MW: 154 kDa; Observed MW: 154 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human Rad50
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IF/ICC	1/50-1/200