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Rabbit Polyclonal Antibody to Wnt5a
-
货号:
P22937 -
别名:
WNT5A; Protein Wnt-5a -
应用:
WB,IF,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P41221 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980
Rabbit Polyclonal Antibody to Wnt5a
Description |
|---|
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. |
Specification |
|
|---|---|
| Aliases | WNT5A; Protein Wnt-5a |
| Entrez GeneID | 7474 |
| Swissprot | P41221 |
| WB Predicted band size | Calculated MW: 42 kDa; Observed MW: 42 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Wnt5a |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IF/ICC | 1/50-1/200 |
| FCM | 1/50-1/100 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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