Rabbit Polyclonal Antibody to Fas

Description
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Specification
Aliases	FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6
Entrez GeneID	355
Swissprot	P25445
WB Predicted band size	Calculated MW: 38 kDa; Observed MW: 48 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human Fas
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100
IF/ICC	1/50-1/200
FCM	1/50-1/100