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Western blot analysis of KMT6 / EZH2 in HEK293 lysates using KMT6 antibody.

Immunofluorescence analysis of KMT6 in Hela using KMT6 / EZH2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using KMT6 / EZH2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Rabbit Polyclonal Antibody to KMT6

货号：
P22880
别名：
WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q15910
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to KMT6

Description
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Description

Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Specification
Aliases	WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2
Entrez GeneID	2146
Swissprot	Q15910
WB Predicted band size	Calculated MW: 85 kDa; Observed MW: 98 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human KMT6 / EZH2
Formulation	Purified antibody in PBS with 0.05% sodium azide.