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Western blot analysis of Cyclin E2 in HeLa lysates using Cyclin E2 antibody.

Immunofluorescence analysis of Cyclin E2 in Hela using Cyclin E2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using Cyclin E2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Rabbit Polyclonal Antibody to Cyclin E2

货号：
P22854
别名：
CCNE2; G1/S-specific cyclin-E2
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,FCM
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
O96020
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to Cyclin E2

Description
The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.

Description

The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.

Specification
Aliases	CCNE2; G1/S-specific cyclin-E2
Entrez GeneID	9134
Swissprot	O96020
WB Predicted band size	Calculated MW: 47 kDa; Observed MW: 47 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthesized peptide derived from human Cyclin E2
Formulation	Purified antibody in PBS with 0.05% sodium azide.