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Western blot analysis of IRF1 in Jurkat lysates using IRF1 antibody.

Immunofluorescence analysis of IRF1 in Hela using IRF1 antibody.

Immunohistochemistry analysis of paraffin-embedded rat kidney using IRF1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Rabbit Polyclonal Antibody to IRF1

货号：
P22793
别名：
IRF1; Interferon regulatory factor 1; IRF-1
产品上架时间：
2024-01-01
应用：
WB,IP,IHC,IF,FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P10914
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to IRF1

Description
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body.

Description

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body.

Specification
Aliases	IRF1; Interferon regulatory factor 1; IRF-1
Entrez GeneID	3659
Swissprot	P10914
WB Predicted band size	Calculated MW: 37 kDa; Observed MW: 48 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human IRF1
Formulation	Purified antibody in PBS with 0.05% sodium azide.