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Western blot analysis of Integrin alpha 5 in K562, 3T3 lysates using Integrin alpha 5 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Integrin alpha 5 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Rabbit Monoclonal Antibody to Integrin alpha 5

货号：
P22709
别名：
ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e
产品上架时间：
2024-01-01
应用：
WB,IP,IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P08648
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to Integrin alpha 5

Description
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.

Description

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.

Specification
Aliases	ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e
Entrez GeneID	3678
Swissprot	P08648
WB Predicted band size	Calculated MW: 115 kDa; Observed MW: 150 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthetic peptide of human Integrin alpha 5
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.