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Western blot analysis of PLK1 in Jurkat, C6 lysates using PLK1 antibody.
Immunocytochemistry analysis of PLK1 (green) in Hela using PLK1 antibody,and DAPI(blue)
HOT

Rabbit Monoclonal Antibody to PLK1

  • 货号:

    P22661
  • 别名:

    PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IF
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P53350
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to PLK1

Description

Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.

Specification

Aliases PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13
Entrez GeneID 5347
Swissprot P53350
WB Predicted band size Calculated MW: 68 kDa; Observed MW: 68 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen A synthetic peptide of human PLK1
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P22661