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Western blot analysis of SV40 Tantigen in A549, HL-60, U251 lysates using SV40 T Antigen antibody.
Immunocytochemistry analysis of SV40 Tantigen (green) in hela using SV40 Tantigen antibody,and DAPI(blue)
HOT

Rabbit Monoclonal Antibody to SV40 T Antigen

  • 货号:

    P22593
  • 别名:

    Large T antigen; LT; LT-AG
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IF
  • 反应种属:

    All
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P03070
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to SV40 T Antigen

Description

Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.

Specification

Aliases Large T antigen; LT; LT-AG
Entrez GeneID 29031019
Swissprot P03070
WB Predicted band size Calculated MW: 82 kDa; Observed MW: 90 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity All
Immunogen A synthetic peptide of SV40 T-antigen
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P22593