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Rabbit Monoclonal Antibody to Notch4
-
货号:
P22233 -
别名:
NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4 -
应用:
WB -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q99466 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Rabbit Monoclonal Antibody to Notch4
Description |
|---|
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity). |
Specification |
|
|---|---|
| Aliases | NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4 |
| Entrez GeneID | 4855 |
| Swissprot | Q99466 |
| WB Predicted band size | Calculated MW: 210 kDa; Observed MW: 36 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human NOTCH4 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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