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Western blot analysis of SATB1 in Hela, A549, HL-60, U2OS lysates using SATB1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using SATB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Rabbit Monoclonal Antibody to SATB1

货号：
P22203
别名：
DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)
产品上架时间：
2024-01-01
应用：
WB,IP,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q01826
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to SATB1

Description
SATB1 is a crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling.

Description

SATB1 is a crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling.

Specification
Aliases	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)
Entrez GeneID	6304
Swissprot	Q01826
WB Predicted band size	Calculated MW: 86 kDa; Observed MW: 100 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human SATB1
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.