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Western blot analysis of Wnt5a in Hela lysates using Wnt5a antibody.
Immunocytochemistry analysis of Wnt5a (green) in hela using Wnt5a antibody,and DAPI(blue)

Rabbit Monoclonal Antibody to Wnt5a

  • 货号:

    P22178
  • 别名:

    WNT5A; Protein Wnt-5a
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P41221
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to Wnt5a

Description

Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.

Specification

Aliases WNT5A; Protein Wnt-5a
Entrez GeneID 7474
Swissprot P41221
WB Predicted band size Calculated MW: 42 kDa; Observed MW: 45 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthetic peptide of human Wnt5a
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P22178