Rabbit Monoclonal Antibody to SPOP

Description
Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.

Specification
Aliases	Speckle-type POZ protein; HIB homolog 1; Roadkill homolog 1
Entrez GeneID	8405
Swissprot	O43791
WB Predicted band size	Calculated MW: 42 kDa; Observed MW: 42 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human SPOP
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application
WB	1/500-1/1000