Rabbit Monoclonal Antibody to SPI1

Description
Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.

Specification
Aliases	SPI1; Transcription factor PU.1; 31 kDa-transforming protein
Entrez GeneID	6688
Swissprot	P17947
WB Predicted band size	Calculated MW: 31 kDa; Observed MW: 42 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthetic peptide of human PU.1/Spi1
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100