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Western blot analysis of PP2A alpha/beta in C2C12, 3T3, mouse brain lysates using PP2A alpha/beta antibody.

Western blot analysis of PP2A alpha/beta in rat Brain, C6, CHO-K1, Hela lysates using PP2A alpha/beta antibody.

Immunocytochemistry analysis of PP2A alpha/beta (green) in hela using PP2A alpha/beta antibody,and DAPI(blue).

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using PP2A alpha/beta antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Rabbit Monoclonal Antibody to PP2A alpha/beta

货号：
P21868
别名：
PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C
产品上架时间：
2024-01-01
应用：
WB,IP,IHC,IF
反应种属：
Human,Mouse,Rat,Hamster
抗体类型：
Primary antibody
Swissprot：
P67775
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to PP2A alpha/beta

Description
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Description

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Specification
Aliases	PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C
Entrez GeneID	5515
Swissprot	P67775
WB Predicted band size	Calculated MW: 36 kDa; Observed MW: 36 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Hamster
Immunogen	A synthetic peptide of human PP2A alpha
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.