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Western blot analysis of NUMB in 3T3, C6, rat Brain, MCF-7 lysates using NUMB antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using NUMB antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Rabbit Monoclonal Antibody to NUMB

货号：
P21774
别名：
NUMB; Protein numb homolog; h-Numb; Protein S171
产品上架时间：
2024-01-01
应用：
WB,IP,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P49757
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to NUMB

Description
Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling.

Specification
Aliases	NUMB; Protein numb homolog; h-Numb; Protein S171
Entrez GeneID	8650
Swissprot	P49757
WB Predicted band size	Calculated MW: 71 kDa; Observed MW: 71 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Recombinant protein of human NUMB
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.