Rabbit Monoclonal Antibody to NRG3

Description
Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.

Specification
Aliases	NRG3; Pro-neuregulin-3; membrane-bound isoform; Pro-NRG3
Entrez GeneID	10718
Swissprot	P56975
WB Predicted band size	Calculated MW: 78 kDa; Observed MW: 55 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	A synthetic peptide of human NRG3
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application
WB	1/500-1/1000