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Mouse Monoclonal Antibody to CD222
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货号:
31642 -
别名:
IGF2R; MPR1; MPRI; CIMPR; M6P-R; MPR300; CI-M6PR; MPR 300; M6P/IGF2R -
产品上架时间:
2024-01-01 -
应用:
-
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P11717 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD222
Description |
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This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015] |
References |
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1.J Diabetes Res. 2015;2015:216383. 2.Cell Physiol Biochem. 2014;34(5):1578-88. |
Specification |
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Aliases | IGF2R; MPR1; MPRI; CIMPR; M6P-R; MPR300; CI-M6PR; MPR 300; M6P/IGF2R |
Entrez GeneID | 3482 |
Swissprot | P11717 |
clone | 7B5E10 |
WB Predicted band size | 274kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31642
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