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Rabbit Monoclonal Antibody to KDM1A
-
货号:
P21599 -
别名:
KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2 -
应用:
WB,IP,IF -
反应种属:
Human,Rat,Hamster -
抗体类型:
Primary antibody -
Swissprot:
O60341 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal Antibody to KDM1A
Description |
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Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. |
Specification |
|
---|---|
Aliases | KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2 |
Entrez GeneID | 23028 |
Swissprot | O60341 |
WB Predicted band size | Calculated MW: 93 kDa; Observed MW: 110 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat,Hamster |
Immunogen | A synthetic peptide of human KDM1/LSD1 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/1000 |
IP | 1/10-1/20 |
IF | 1/50-1/200 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P21599

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