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Western blot analysis of KDM1/LSD1 in Jurkat lysates using KDM1A antibody.
Western blot analysis of KDM1/LSD1 in Hela, CHO-K1, C6, Jurkat lysates using KDM1/LSD1 antibody.
Immunocytochemistry analysis of KDM4B/JMJD2B(green) in Hela using KDM4B/JMJD2B antibody,and DAPI(blue)
HOT

Rabbit Monoclonal Antibody to KDM1A

  • 货号:

    P21599
  • 别名:

    KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
  • 产品上架时间:

    2024-03-02
  • 应用:

    WB,IP,IF
  • 反应种属:

    Human,Rat,Hamster
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O60341
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to KDM1A

Description

Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.

Specification

Aliases KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
Entrez GeneID 23028
Swissprot O60341
WB Predicted band size Calculated MW: 93 kDa; Observed MW: 110 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat,Hamster
Immunogen A synthetic peptide of human KDM1/LSD1
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P21599