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Western blot analysis of HP1 alpha in C6, PC-12 lysates using HP1 alpha antibody.

Western blot analysis of HP1 alpha in 3T3, Hela lysates using HP1 alpha antibody.

Immunocytochemistry analysis of HP1 alpha(green) in Hela using HP1 alpha antibody,and DAPI(blue)

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using HP1 alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Rabbit Monoclonal Antibody to HP1 alpha

货号：
P21521
别名：
CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
产品上架时间：
2024-01-01
应用：
WB,IP,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P45973
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to HP1 alpha

Description
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Description

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Specification
Aliases	CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
Entrez GeneID	23468
Swissprot	P45973
WB Predicted band size	Calculated MW: 22 kDa; Observed MW: 22 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic peptide of human HP1 alpha
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.