Rabbit Monoclonal Antibody to Histone H2A.X

Description
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Specification
Aliases	H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X
Entrez GeneID	3014
Swissprot	P16104
WB Predicted band size	Calculated MW: 15 kDa; Observed MW: 15 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic peptide of human Histone H2A.X
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application
WB	1/500-1/1000
IP	1/10-1/20
IHC	1/50-1/100
IF	1/50-1/200