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Western blot analysis using LSD1 mouse mAb against COS (1), Hela (2), NIH/3T3 (3), A549 (4) and Jurkat (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma (left) and kidney carcinoma (right), showing nuclear localization using LSD1 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to LSD1/AOF2

货号：
20055
别名：
KDM1; LSD1; AOF2
产品上架时间：
2024-05-01
应用：
WB,IHC
反应种属：
Human,Mouse,Monkey
抗体类型：
Primary antibody
Swissprot：
O60341
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to LSD1/AOF2

Description
The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

Description

The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

References
1. Shi YJ, et.al Mol Cell. 2005 Sep 16;19(6):857-64. 2. Metzger E, et.al Nature. 2005 Sep 15;437(7057):436-9.

Specification
Aliases	KDM1; LSD1; AOF2
Entrez GeneID	23028
Swissprot	O60341
clone	1B2E5
WB Predicted band size	93kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Monkey
Immunogen	Purified recombinant fragment of human LSD1 expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.