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Western blot analysis of Estrogen Receptor alpha in K562, Hela lysates using Estrogen Receptor alpha antibody.
Immunocytochemistry analysis of Estrogen Receptor alpha (green) in MCF-7 using Estrogen Receptor alpha antibody,and DAPI(blue)
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Estrogen Receptor alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Rabbit Monoclonal Antibody to Estrogen Receptor alpha

  • 货号:

    P21367
  • 别名:

    ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P03372
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to Estrogen Receptor alpha

Description

ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

Specification

Aliases ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha
Entrez GeneID 2099
Swissprot P03372
WB Predicted band size Calculated MW: 66 kDa; Observed MW: 66 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthetic peptide of human Estrogen Receptor alpha
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
IF 1/50-1/200