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Western blot analysis of CDKN2A/p16INK4a in 3T3 lysates using CDKN2A antibody.
Western blot analysis of CDKN2A/p16INK4a in C6 lysates using CDKN2A/p16INK4a antibody.
HOT

Rabbit Monoclonal Antibody to CDKN2A/p16INK4a

  • 货号:

    P21211
  • 别名:

    Cdkn2a;P16ink4a;Cyclin-dependent kinase 4 inhibitor A (CDK4I);p16-INK4a ;p16-INK4
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IF
  • 反应种属:

    Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P51480
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to CDKN2A/p16INK4a

Description

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.CautionThe proteins described here are encoded by the gene CDKN2A, but are completely unrelated in terms of sequence and function to tumor suppressor ARF (AC Q64364) which is encoded by the same gene.

Specification

Aliases Cdkn2a;P16ink4a;Cyclin-dependent kinase 4 inhibitor A (CDK4I);p16-INK4a ;p16-INK4
Entrez GeneID 12578
Swissprot P51480
WB Predicted band size Calculated MW: 18 kDa; Observed MW: 18 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse,Rat
Immunogen Recombinant protein of mouse CDKN2A/p16INK4a
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P21211