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Western blot analysis of BACE1 in rat Brain lysates using BACE1 antibody.
HOT

Rabbit Monoclonal Antibody to BACE1

  • 货号:

    P21107
  • 别名:

    ASP2; Bace; C76936
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP
  • 反应种属:

    Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P56818
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to BACE1

Description

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.

Specification

Aliases ASP2; Bace; C76936
Entrez GeneID 23821
Swissprot P56818
WB Predicted band size Calculated MW: 56 kDa; Observed MW: 70 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Rat
Immunogen Recombinant protein of mouse BACE1
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P21107