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Rabbit Monoclonal Antibody to BACE1
-
货号:
P21107 -
别名:
ASP2; Bace; C76936 -
应用:
WB,IP -
反应种属:
Rat -
抗体类型:
Primary antibody -
Swissprot:
P56818 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Rabbit Monoclonal Antibody to BACE1
Description |
|---|
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type. |
Specification |
|
|---|---|
| Aliases | ASP2; Bace; C76936 |
| Entrez GeneID | 23821 |
| Swissprot | P56818 |
| WB Predicted band size | Calculated MW: 56 kDa; Observed MW: 70 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Rat |
| Immunogen | Recombinant protein of mouse BACE1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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