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Western blot analysis of ATM in Hela, 293 lysates using ATM antibody.
Immunocytochemistry analysis of ATM (green) in HT-1080 using ATM antibody,and DAPI(blue).
HOT
Rabbit Monoclonal Antibody to ATM
-
货号：
P20897 -
别名：
ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated -
应用：
WB,IF -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q13315 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Monoclonal Antibody to ATM
Description |
|---|
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. |
Specification |
|
|---|---|
| Aliases | ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated |
| Entrez GeneID | 472 |
| Swissprot | Q13315 |
| WB Predicted band size | Calculated MW: 351 kDa; Observed MW: 351 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human ATM |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IF | 1/50-1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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