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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Flow cytometric analysis of Ramos cells using CD120B mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to CD120B

货号：
31555
别名：
TNFRSF1B; p75; TBPII; TNFBR; TNFR2; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
产品上架时间：
2024-01-01
应用：
FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P20333
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Description

References
1.Clin Exp Immunol. 2016 Aug;185(2):263-70. 2.Cancer Immunol Immunother. 2015 Nov;64(11):1475-85.

Specification
Aliases	TNFRSF1B; p75; TBPII; TNFBR; TNFR2; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
Entrez GeneID	7133
Swissprot	P20333
clone	7G8B6
WB Predicted band size	48.3kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human CD120B (AA: extra 23-257) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide