Mouse Monoclonal Antibody to CD339

Description
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

References
1.Cancer Sci. 2016 Nov;107(11):1705-1716. 2.Gene. 2016 Jan 15;576(1 Pt 3):381-4.

Specification
Aliases	JAG1; AGS; AHD; AWS; HJ1; AGS1; JAGL1
Entrez GeneID	182
Swissprot	P78504
clone	7C7E1
WB Predicted band size	133.8kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human CD339 (AA: extra 47-212) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500 - 1/2000
FCM	1/200 - 1/400
ELISA	1/10000