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Western blot analysis of CD45 in Jurkat lysates using CD45 antibody.
Immunofluorescence analysis of CD45 in Human livercancer tissue using CD45 antibody(red),and DAPI (blue).
Immunohistochemical analysis of paraffin-embedded Human tonsils using CD45 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only.

Mouse Monoclonal Antibody to CD45

  • 货号:

    P20769
  • 别名:

    GP180; L CA; CD45 antigen
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P08575
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CD45

Description

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.

Specification

Aliases GP180; L CA; CD45 antigen
Entrez GeneID 19264
Swissprot P08575
clone 9D3
WB Predicted band size Calculated MW: 145 kDa; Observed MW: 145 kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic Peptide of CD45
Formulation Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/50-1/200