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Western blot analysis of EGFR in A549, MDA-MB-468 and COS7 lysates using EGFR antibody.
Immunoprecipitation analysis of EGFR in Hela lysates using EGFR antibody.
Immunocytochemistry analysis of EGFR in HeLa using EGFR antibody.
Immunocytochemistry analysis of EGFR in MDA-MB-468 cells using EGFR antibody.

Mouse Monoclonal Antibody to EGFR

  • 货号:

    P20743
  • 别名:

    EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IF
  • 反应种属:

    Human,Monkey
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P00533
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to EGFR

Description

EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Specification

Aliases EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Entrez GeneID 1956
Swissprot P00533
clone 8B1
WB Predicted band size Calculated MW: 134 kDa; Observed MW: 175 kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Monkey
Immunogen Purified recombinant human EGFR protein fragments expressed in E.coli.
Formulation Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P20743