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Mouse Monoclonal Antibody to CD148
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货号:
31543 -
别名:
PTPRJ; DEP1; SCC1; HPTPeta; R-PTP-ETA -
产品上架时间:
2024-01-01 -
应用:
FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q12913 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD148
Description |
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. |
References |
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1.Oncogene. 2015 Oct 29;34(44):5536-47. 2.J Neurooncol. 2015 May;122(3):451-9. |
Specification |
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Aliases | PTPRJ; DEP1; SCC1; HPTPeta; R-PTP-ETA |
Entrez GeneID | 5795 |
Swissprot | Q12913 |
clone | 1D2C11 |
WB Predicted band size | 146kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD148 (AA: extra 36-210) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31543
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