Mouse Monoclonal Antibody to CHD3

Description
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.

Specification
Aliases	CHD3; Chromodomain-helicase-DNA-binding protein 3; CHD-3; ATP-dependent helicase CHD3; Mi-2 autoantigen 240 kDa protein; Mi2-alpha; Zinc finger helicase; hZFH
Entrez GeneID	1107
Swissprot	Q12873
clone	8H7
WB Predicted band size	Calculated MW: 227 kDa; Observed MW: 260 kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Purified recombinant human CHD3 (C-terminus) protein fragments expressed in E.coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application
WB	1/500-1/1000
IP	1/10-1/20
IF	1/50-1/200